Fundamental study on cancer therapy by blocking newborn blood vessels with surface modified magnetite particles

We propose a novel cancer treatment which involves blocking newborn blood vessels around the diseased part. This has minimal side effects and is less invasive. In therapy, ferromagnetic particles administered into body are accumulated in vessels. Next, aggregated to block prevent growth metastasis. this study, we modified surface of magnetite with biocompatible polyacrylic acid design that form irreversible aggregation on application magnetic field. succeeded only flow path under uniform field using prepared particles, as verified by results model experiment. assume blockage occurred due formation chain increase pressure loss.